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Post mortem analysis of AD patients revealed unusually high levels of these metal ions in the senile plaques [Cu 2+ (393 μM), Zn 2+ (1055μM) and Fe 3+ (940μM)] compared to a healthy person [Cu 2+ (70 μM), Zn 2+ (350μM) and Fe 3+ (340μM)] [206, 207]

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Taking B12 with or without food makes little difference for standard oral supplements in individuals with normal gastrointestinal function