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5.2 Potent antioxidant role in follicular fluid, oocytes, and granulosa cells As mentioned earlier, follicular fluid has higher amounts of melatonin when compared to blood, and this is solely owing to the fact that melatonin can be produced locally in the ovary (187)

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A fresh vial with confirmed proper storage can help you determine if dosing needs to change or if the problem was storage all along