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Although the mechanisms underlying increased GSNO reductase activity in asthma are not clear, recent studies have demonstrated increased GSNO reductase activity in response to formaldehyde (303, 316), which is increased in the airways of asthmatics versus controls (as formate) and is associated with airway hyperreactivity and asthma severity in a concentration-dependent manner (116)

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Curcumin ameliorates cadmium-induced nephrotoxicity in Sprague-Dawley rats