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Protection and Healing in the Digestive System and Other Tissues: Novel Factors, Mechanisms, and Pharmaceutical Targets | Frontiers Research Topic

A.ZefenkeyZ

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It upregulates genes involved in: Collagen and extracellular matrix production Antioxidant defense systems DNA repair mechanisms Ubiquitin-proteasome system (cellular protein quality control) Stem cell function Simultaneously, it suppresses genes associated with: Chronic inflammation Tissue destruction (matrix metalloproteinases) Fibrosis and scarring Insulin resistance This broad gene modulation is unusual for a single compound and may explain GHK-Cu's wide range of anti-aging effects