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CMX001 Alkoxyalkyl esters of cidofovir (CDV) such as hexadecy-loxypropyl CDV (CMX001) were developed to improve oral bioavailability of CDV Fig

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Basic research supports this mechanism, demonstrating that fructose or HFD exposure induces mitochondrial structural abnormalities, mtDNA depletion, and ATP deficiency, ultimately impairing β-oxidation and hepatocyte function

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