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The animals underwent a sciatic nerve repair model that began with the transection of the main sciatic nerve above the trifurcation point into the tibial, fibular, and sural branches

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Loliolide (20 μg/mL) significantly increased the size of HDP spheroids in 3D culture and enhanced the expression of growth factors, such as vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), and keratinocyte growth factor (KGF) in HDP spheroids