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The colon mucosa of rats showed marked inhibition of histological damages, pro-inflammatory cytokines and elevation of protein (pNFκB p65) via down regulation of NF-κB pathway [113]

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Engineering and systems-medicine perspective: On the one hand, diet-based interventions, with the addition of pharmacological ferroptosis inhibitors have the potential to act synergistically to delay or prevent ferroptosis-mediated neurodegenerative mechanisms