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These include capsaicin (reduces the level of a pain transmitter called Substance P), SAMe or S-adenosylmethionine (an endogenous compound that stimulates cartilage production), and anthocyanidins (an antioxidant that prevent the degradation of collagen)

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Shrott, MD, of Cleveland Clinic, B12 injections reliably correct deficiency symptoms but offer little measurable benefit to people whose levels are already normal