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People who were overweight or obese lost significant weight while taking retatrutide, which enabled them to be more active and reduced knee pain by an average of 4.5 points or about 76% based on pain scores from what’s known as the Western Ontario and McMaster Universities Osteoarthritis Index

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cDNA was synthesized with the iScript™ cDNA Synthesis Kit (#170-8891, Biorad) and subjected to quantitative real-time PCR using SYBR Green Supermix (#172-5272, Biorad)