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A subsequent 2014 paper by Chang and colleagues in Molecules showed that BPC-157, applied at 0.1–0.5 µg/mL in vitro, dose- and time-dependently upregulated growth hormone receptor expression at both mRNA and protein levels in cultured rat Achilles tendon fibroblasts — a mechanistic in vitro finding for which numeric fold-changes and p-values are not reported in the abstract

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Room temperature represents just one option on a spectrum from frozen storage to elevated temperature stress