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Notably, the inhibition of ACSL4 has been shown to reduce the incidence of neuronal ferroptosis, indicating that ACSL4 could be a viable target for the treatment of bone-related disorders (45)

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The screening was performed at 10 µM inhibitor concentration, except in those cases marked with an asterisk, which were assayed at 1 µM (at 10 µM control experiments for these compounds without enzyme showed non-constant base lines)