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Because the amylin receptors are heterodimers of the calcitonin receptor with different RAMP partners, researchers studying RAMP biology, calcitonin receptor pharmacology, and the broader class B GPCR family use cagrilintide as a reference agonist

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Any elderly patient experiencing new or worsening neurological symptoms despite B12 treatment should be referred back to their GP for reassessment, as alternative diagnoses must be considered