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Measurement of IGF-1 by MSIA-SRM
Cystine can be sequentially converted into GSH, which is indispensable in maintaining the intracellular redox balance as it can be utilized by GPX4 as a cofactor to alleviate lipid peroxidation (LPO) [32, 33] (Fig
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52,53,54 In contrast, in conditions such as chronic obstructive pulmonary disease, 55 idiopathic pulmonary fibrosis, 56 hypertension, 57 type II diabetes, 58 neurodegenerative diseases, 59 cancer, 13 and systemic inflammatory response syndrome, 60 redox regulation indirectly influences disease progression through signal transduction pathways